IUBMB Enzyme Nomenclature

EC 3.5.99.7

Accepted name: 1-aminocyclopropane-1-carboxylate deaminase

Reaction: 1-aminocyclopropane-1-carboxylate + H2O = 2-oxobutanoate + NH3

Other name(s): 1-aminocyclopropane-1-carboxylate endolyase (deaminating)

Systematic name: 1-aminocyclopropane-1-carboxylate aminohydrolase (isomerizing)

Comments: A pyridoxal 5'-phosphate enzyme. Its introduction has been used to make fruit ripening dependent on externally added ethylene, as it removes the substrate for endogenous ethylene formation.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, PDB, UM-BBD, CAS registry number: 69553-48-6

References:

1. Honma, M. and Shimomura T. Metabolism of 1-aminocyclopropane-1-carboxylic acid. Agric. Biol. Chem. 42 (1978) 1825-1831.

2. Yao, M., Ose, T., Sugimoto, H., Horiuchi, A., Nakagawa, A., Wakatsuki, S., Yokoi, D., Murakami, T., Honma, M. and Tanaka, I. Crystal structure of 1-aminocyclopropane-1-carboxylate deaminase from Hansenula saturnus. J. Biol. Chem. 275 (2000) 34557-34565. [PMID: 10938279]

[EC 3.5.99.7 created 1981 as EC 4.1.99.4, transferred 2002 to EC 3.5.99.7]


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