Reaction: NTP + H2O = NDP + phosphate
Glossary: thiamine diphosphate
Other name(s): nucleoside triphosphate phosphohydrolase; nucleoside-5-triphosphate phosphohydrolase; nucleoside 5-triphosphatase
Systematic name: unspecific diphosphate phosphohydrolase
Comments: Also hydrolyses other nucleoside triphosphates, diphosphates, thiamine diphosphate and FAD.
Links to other databases: BRENDA, EXPASY, KEGG, PDB, CAS registry number: 9075-51-8
References:
1. Brightwell, R. and Tappel, A.L. Lysosomal acid pyrophosphatase and acid phosphatase. Arch. Biochem. Biophys. 124 (1968) 333-343. [PMID: 5661608]
2. Lewis, M. and Weissman, S. Properties of a soluble nucleoside triphosphatase activity in mammalian liver. Arch. Biochem. Biophys. 109 (1965) 490-498.
3. Matsushita, S. and Raacke, I.D. Purification of nucleoside triphosphatases from pea seedling ribosomes. Biochim. Biophys. Acta 166 (1968) 707-710. [PMID: 4301913]