IUBMB Enzyme Nomenclature


Accepted name: NAD+ diphosphatase

Reaction: NAD+ + H2O = AMP + NMN

Other name(s): nicotinamide adenine dinucleotide pyrophosphatase; NADP pyrophosphatase; NADH pyrophosphatase

Systematic name: NAD+ phosphohydrolase

Comments: Also acts on NADP+, 3-acetylpyridine and the thionicotinamide analogues of NAD+ and NADP+.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, PDB, CAS registry number: 37289-33-1


1. Anderson, B.M. and Lang, C.A. Nicotinamide-adenine dinucleotide pyrophosphatase in the growing and aging mosquito. Biochem. J. 101 (1966) 392-396. [PMID: 4381708]

2. Nakajima, Y., Fukunaga, N., Sasaki, S. and Usami, S. Preparation and properties of NADP pyrophosphatase from Proteus vulgaris. Biochim. Biophys. Acta 293 (1973) 242-255.

[EC created 1972]

Return to EC 3.6.1 home page
Return to EC 3.6 home page
Return to EC 3 home page
Return to Enzymes home page
Return to IUBMB Biochemical Nomenclature home page