Reaction: 7-methylguanosine 5'-triphospho-5'-polynucleotide + H2O = 7-methylguanosine 5'-phosphate + polynucleotide
Other name(s): decapase; m7G(5')pppN pyrophosphatase
Systematic name: 7-methylguanosine-5'-triphospho-5'-polynucleotide 7-methylguanosine-5'-phosphohydrolase
Links to other databases: BRENDA, EXPASY, KEGG, CAS registry number: 82599-75-5
References:
1. Lavers, G.C. Cleavage of pm7G from mRNA 5' terminal cap structures by pyrophosphatase activity in embryonic chick lens cells. Mol. Biol. Rep. 3 (1977) 413-420. [PMID: 593271]
2. Nuss, D.L., Alschuler, R.E. and Peterson, A.J. Purification and characterization of the m7G(5')pppN-pyrophosphatase from human placenta. J. Biol. Chem. 257 (1982) 6224-6230. [PMID: 6122684]
3. Nuss, D.L. and Furuichi, Y. Characterization of the m7G(5')pppN-pyrophosphatase activity from HeLa cells. J. Biol. Chem. 252 (1977) 2815-2821. [PMID: 16003]