Reaction: A nucleoside diphosphate + H2O = a nucleotide + phosphate
Other name(s): thiaminpyrophosphatase; UDPase; inosine diphosphatase; adenosine diphosphatase; IDPase; ADPase; adenosinepyrophosphatase; guanosine diphosphatase; guanosine 5'-diphosphatase; inosine 5'-diphosphatase; uridine diphosphatase; uridine 5'-diphosphatase; nucleoside diphosphate phosphatase; type B nucleoside diphosphatase; GDPase; CDPase; nucleoside 5'-diphosphatase; type L nucleoside diphosphatase; NDPase; nucleoside diphosphate phosphohydrolase
Systematic name: nucleoside-diphosphate phosphohydrolase
Comments: Acts on IDP, GDP, UDP and also on D-ribose 5-diphosphate
Links to other databases: BRENDA, EXPASY, KEGG, CAS registry number: 9027-69-4
References:
1. Gibson, D.M., Ayengar, P. and Sanadi, D.R. A phosphatase specific for nucleoside diphosphates. Biochim. Biophys. Acta 16 (1955) 536-538.
2. Horecker, B.L., Hurwitz, J. and Heppel, L.A. The synthesis of ribose 5-pyrophosphate and ribose 5-triphosphate. J. Am. Chem. Soc. 79 (1957) 701-702.