IUBMB Enzyme Nomenclature

EC 3.6.3.12

Accepted name: K+-transporting ATPase

Reaction: ATP + H2O + K+out = ADP + phosphate + K+in

Other name(s): K+-translocating Kdp-ATPase; multi-subunit K+-transport ATPase

Systematic name: ATP phosphohydrolase (K+-importing)

Comments: A P-type ATPase that undergoes covalent phosphorylation during the transport cycle. A bacterial enzyme of di(heterotetrameric) structure that is involved in K+ import. The probable stoichiometry is one ion per ATP hydrolysed.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, PDB, CAS registry number:

References:

1. Siebers, A. and Altendorf, K. Characterization of the phosphorylated intermediate of the K+-translocating Kdp-ATPase from Escherichia coli. J. Biol. Chem 264 (1989) 5831-5838. [PMID: 2522440]

2. Gassel, M., Siebers, A., Epstein, W. and Altendorf, K. Assembly of the Kdp complex, the multi-subunit K+-transport ATPase of Escherichia coli. Biochim. Biophys. Acta 1415 (1998) 77-84. [PMID: 9858692]

[EC 3.6.3.12 created 2000]


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