IUBMB Enzyme Nomenclature

EC 3.6.4.11

Accepted name: nucleoplasmin ATPase

Reaction: ATP + H2O = ADP + phosphate

Systematic name: ATP phosphohydrolase (nucleosome-assembling)

Comments: An acidic nuclear protein that is active in the ATP-dependent assembly of nucleosome cores, in decondensation of sperm chromatin and in other histone-involving processes.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number:

References:

1. Laskey, R.A., Mills, A.D., Philpott, A., Leno, G.H., Dilworth, S.M. and Dingwall, C. The role of nucleoplasmin in chromatin assembly and disassembly. Phil. Trans. R. Soc. London B Biol. Sci. 339 (1993) 263-269. [PMID: 8098530]

2. Cote, J., Quinn, J., Workman, J.L. and Peterson, C.L. Stimulation of GAL4 derivative binding to nucleosomal DNA by the yeast SWI/SNF complex. Science 265 (1994) 53-60. [PMID: 8016655]

3. Ito, T., Tyler, J.K., Bulger, M., Kobayashi, R. and Kadonaga, J.T. ATP-facilitated chromatin assembly with a nucleoplasmin-like protein from Drosophila melanogaster. J. Biol. Chem 271 (1996) 25041-25048. [PMID: 8798787]

[EC 3.6.4.11 created 2000]


Return to EC 3.6.4 home page
Return to EC 3.6 home page
Return to EC 3 home page
Return to Enzymes home page
Return to IUBMB Biochemical Nomenclature home page