Nomenclature Committee of the International Union of Biochemistry and Molecular Biology (NC-IUBMB)

Enzyme Nomenclature. Recommendations

Contents EC 3.1 - EC 3.3

EC 3. Hydrolases

EC 3.1 Acting on Ester Bonds

EC 3.1.1 Carboxylic Ester Hydrolases

EC 3.1.1.1 carboxylesterase
EC 3.1.1.2 arylesterase
EC 3.1.1.3 triacylglycerol lipase
EC 3.1.1.4 phospholipase A2
EC 3.1.1.5 lysophospholipase
EC 3.1.1.6 acetylesterase
EC 3.1.1.7 acetylcholinesterase
EC 3.1.1.8 cholinesterase
EC 3.1.1.9 deleted
EC 3.1.1.10 tropinesterase
EC 3.1.1.11 pectinesterase
EC 3.1.1.12 deleted
EC 3.1.1.13 sterol esterase
EC 3.1.1.14 chlorophyllase
EC 3.1.1.15 L-arabinonolactonase
EC 3.1.1.16 deleted, mixture of EC 5.3.3.4 and EC 3.1.1.24
EC 3.1.1.17 gluconolactonase
EC 3.1.1.18 deleted, included in EC 3.1.1.17
EC 3.1.1.19 uronolactonase
EC 3.1.1.20 tannase
EC 3.1.1.21 deleted, catalysed by EC 3.1.1.1 and EC 3.1.1.3
EC 3.1.1.22 hydroxybutyrate-dimer hydrolase
EC 3.1.1.23 acylglycerol lipase
EC 3.1.1.24 3-oxoadipate enol-lactonase
EC 3.1.1.25 1,4-lactonase
EC 3.1.1.26 galactolipase
EC 3.1.1.27 4-pyridoxolactonase
EC 3.1.1.28 acylcarnitine hydrolase
EC 3.1.1.29 aminoacyl-tRNA hydrolase
EC 3.1.1.30 D-arabinonolactonase
EC 3.1.1.31 6-phosphogluconolactonase
EC 3.1.1.32 phospholipase A1
EC 3.1.1.33 6-acetylglucose deacetylase
EC 3.1.1.34 lipoprotein lipase
EC 3.1.1.35 dihydrocoumarin hydrolase
EC 3.1.1.36 limonin-D-ring-lactonase
EC 3.1.1.37 steroid-lactonase
EC 3.1.1.38 triacetate-lactonase
EC 3.1.1.39 actinomycin lactonase
EC 3.1.1.40 orsellinate-depside hydrolase
EC 3.1.1.41 cephalosporin-C deacetylase
EC 3.1.1.42 chlorogenate hydrolase
EC 3.1.1.43 α-amino-acid esterase
EC 3.1.1.44 4-methyloxaloacetate esterase
EC 3.1.1.45 carboxymethylenebutenolidase
EC 3.1.1.46 deoxylimonate A-ring-lactonase
EC 3.1.1.47 1-alkyl-2-acetylglycerophosphocholine esterase
EC 3.1.1.48 fusarinine-C ornithinesterase
EC 3.1.1.49 sinapine esterase
EC 3.1.1.50 wax-ester hydrolase
EC 3.1.1.51 phorbol-diester hydrolase
EC 3.1.1.52 phosphatidylinositol deacylase
EC 3.1.1.53 sialate O-acetylesterase
EC 3.1.1.54 acetoxybutynylbithiophene deacetylase
EC 3.1.1.55 acetylsalicylate deacetylase
EC 3.1.1.56 methylumbelliferyl-acetate deacetylase
EC 3.1.1.57 2-pyrone-4,6-dicarboxylate lactonase
EC 3.1.1.58 N-acetylgalactosaminoglycan deacetylase
EC 3.1.1.59 juvenile-hormone esterase
EC 3.1.1.60 bis(2-ethylhexyl)phthalate esterase
EC 3.1.1.61 protein-glutamate methylesterase
EC 3.1.1.62 now EC 3.5.1.47
EC 3.1.1.63 11-cis-retinyl-palmitate hydrolase
EC 3.1.1.64 retinoid isomerohydrolase
EC 3.1.1.65 L-rhamnono-1,4-lactonase
EC 3.1.1.66 5-(3,4-diacetoxybut-1-ynyl)-2,2'-bithiophene deacetylase
EC 3.1.1.67 fatty-acyl-ethyl-ester synthase
EC 3.1.1.68 xylono-1,4-lactonase
EC 3.1.1.69 now EC 3.5.1.89
EC 3.1.1.70 cetraxate benzylesterase
EC 3.1.1.71 acetylalkylglycerol acetylhydrolase
EC 3.1.1.72 acetylxylan esterase
EC 3.1.1.73 feruloyl esterase
EC 3.1.1.74 cutinase
EC 3.1.1.75 poly(3-hydroxybutyrate) depolymerase
EC 3.1.1.76 poly(3-hydroxyoctanoate) depolymerase
EC 3.1.1.77 acyloxyacyl hydrolase
EC 3.1.1.78 polyneuridine-aldehyde esterase
EC 3.1.1.79 hormone-sensitive lipase
EC 3.1.1.80 acetylajmaline esterase
EC 3.1.1.81 quorum-quenching N-acyl-homoserine lactonase
EC 3.1.1.82 pheophorbidase
EC 3.1.1.83 monoterpene ε-lactone hydrolase
EC 3.1.1.84 cocaine esterase
EC 3.1.1.85 pimelyl-[acyl-carrier protein] methyl ester esterase
EC 3.1.1.86 rhamnogalacturonan acetylesterase
EC 3.1.1.87 fumonisin B1 esterase
EC 3.1.1.88 pyrethroid hydrolase
EC 3.1.1.89 protein phosphatase methylesterase-1
EC 3.1.1.90 all-trans-retinyl ester 13-cis isomerohydrolase
EC 3.1.1.91 2-oxo-3-(5-oxofuran-2-ylidene)propanoate lactonase
EC 3.1.1.92 4-sulfomuconolactone hydrolase
EC 3.1.1.93 mycophenolic acid acyl-glucuronide esterase
EC 3.1.1.94 versiconal hemiacetal acetate esterase
EC 3.1.1.95 aclacinomycin methylesterase
EC 3.1.1.96 D-aminoacyl-tRNA deacylase
EC 3.1.1.97 methylated diphthine methylhydrolase
EC 3.1.1.98 [Wnt protein] O-palmitoleoyl-L-serine hydrolase
EC 3.1.1.99 6-deoxy-6-sulfogluconolactonase
EC 3.1.1.100 chlorophyllide a hydrolase
EC 3.1.1.101 poly(ethylene terephthalate) hydrolase
EC 3.1.1.102 mono(ethylene terephthalate) hydrolase

EC 3.1.2 Thioester Hydrolases

EC 3.1.2.1 acetyl-CoA hydrolase
EC 3.1.2.2 palmitoyl-CoA hydrolase
EC 3.1.2.3 succinyl-CoA hydrolase
EC 3.1.2.4 3-hydroxyisobutyryl-CoA hydrolase
EC 3.1.2.5 hydroxymethylglutaryl-CoA hydrolase
EC 3.1.2.6 hydroxyacylglutathione hydrolase
EC 3.1.2.7 glutathione thiolesterase
EC 3.1.2.8 deleted, included in EC 3.1.2.6
EC 3.1.2.9 deleted
EC 3.1.2.10 formyl-CoA hydrolase
EC 3.1.2.11 acetoacetyl-CoA hydrolase
EC 3.1.2.12 S-formylglutathione hydrolase
EC 3.1.2.13 S-succinylglutathione hydrolase
EC 3.1.2.14 oleoyl-[acyl-carrier-protein] hydrolase
EC 3.1.2.15 deleted
EC 3.1.2.16 citrate lyase deacetylase
EC 3.1.2.17 (S)-methylmalonyl-CoA hydrolase
EC 3.1.2.18 ADP-dependent short-chain-acyl-CoA hydrolase
EC 3.1.2.19 ADP-dependent medium-chain-acyl-CoA hydrolase
EC 3.1.2.20 acyl-CoA hydrolase
EC 3.1.2.21 dodecanoyl-[acyl-carrier protein] hydrolase
EC 3.1.2.22 palmitoyl[protein] hydrolase
EC 3.1.2.23 4-hydroxybenzoyl-CoA thioesterase
EC 3.1.2.24 transferred entry now EC 3.13.1.3
EC 3.1.2.25 phenylacetyl-CoA hydrolase
EC 3.1.2.26 transferred now EC 2.8.3.25
EC 3.1.2.27 choloyl-CoA hydrolase
EC 3.1.2.28 1,4-dihydroxy-2-naphthoyl-CoA hydrolase
EC 3.1.2.29 fluoroacetyl-CoA thioesterase
EC 3.1.2.30 (3S)-malyl-CoA thioesterase

EC 3.1.2.31 dihydromonacolin L-[lovastatin nonaketide synthase] thioesterase
EC 3.1.2.32 2-aminobenzoylacetyl-CoA thioesterase

EC 3.1.3 Phosphoric Monoester Hydrolases

EC 3.1.3.1 alkaline phosphatase
EC 3.1.3.2 acid phosphatase
EC 3.1.3.3 phosphoserine phosphatase
EC 3.1.3.4 phosphatidate phosphatase
EC 3.1.3.5 5'-nucleotidase
EC 3.1.3.6 3'-nucleotidase
EC 3.1.3.7 3'(2'),5'-bisphosphate nucleotidase
EC 3.1.3.8 3-phytase
EC 3.1.3.9 glucose-6-phosphatase
EC 3.1.3.10 glucose-1-phosphatase
EC 3.1.3.11 fructose-bisphosphatase
EC 3.1.3.12 trehalose-phosphatase
EC 3.1.3.13 deleted now covered by EC 5.4.2.11
EC 3.1.3.14 methylphosphothioglycerate phosphatase
EC 3.1.3.15 histidinol-phosphatase
EC 3.1.3.16 protein-serine/threonine phosphatase
EC 3.1.3.17 [phosphorylase] phosphatase
EC 3.1.3.18 phosphoglycolate phosphatase
EC 3.1.3.19 glycerol-2-phosphatase
EC 3.1.3.20 phosphoglycerate phosphatase
EC 3.1.3.21 glycerol-1-phosphatase
EC 3.1.3.22 mannitol-1-phosphatase
EC 3.1.3.23 sugar-phosphatase
EC 3.1.3.24 sucrose-phosphate phosphatase
EC 3.1.3.25 inositol-phosphate phosphatase
EC 3.1.3.26 4-phytase
EC 3.1.3.27 phosphatidylglycerophosphatase
EC 3.1.3.28 ADPphosphoglycerate phosphatase
EC 3.1.3.29 N-acylneuraminate-9-phosphatase
EC 3.1.3.30 deleted, included in EC 3.1.3.31
EC 3.1.3.31 nucleotidase
EC 3.1.3.32 polynucleotide 3'-phosphatase
EC 3.1.3.33 polynucleotide 5'-phosphatase
EC 3.1.3.34 deoxynucleotide 3'-phosphatase
EC 3.1.3.35 thymidylate 5'-phosphatase
EC 3.1.3.36 phosphoinositide 5-phosphatase
EC 3.1.3.37 sedoheptulose-bisphosphatase
EC 3.1.3.38 3-phosphoglycerate phosphatase
EC 3.1.3.39 streptomycin-6-phosphatase
EC 3.1.3.40 guanidinodeoxy-scyllo-inositol-4-phosphatase
EC 3.1.3.41 4-nitrophenylphosphatase
EC 3.1.3.42 [glycogen-synthase-D] phosphatase
EC 3.1.3.43 [pyruvate dehydrogenase (acetyl-transferring)]-phosphatase
EC 3.1.3.44 [acetyl-CoA carboxylase]-phosphatase
EC 3.1.3.45 3-deoxy-manno-octulosonate-8-phosphatase
EC 3.1.3.46 fructose-2,6-bisphosphate 2-phosphatase
EC 3.1.3.47 [hydroxymethylglutaryl-CoA reductase (NADPH)]-phosphatase
EC 3.1.3.48 protein-tyrosine-phosphatase
EC 3.1.3.49 [pyruvate kinase]-phosphatase
EC 3.1.3.50 sorbitol-6-phosphatase
EC 3.1.3.51 dolichyl-phosphatase
EC 3.1.3.52 [3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)]-phosphatase
EC 3.1.3.53 [myosin-light-chain] phosphatase
EC 3.1.3.54 fructose-2,6-bisphosphate 6-phosphatase
EC 3.1.3.55 caldesmon-phosphatase
EC 3.1.3.56 inositol-polyphosphate 5-phosphatase
EC 3.1.3.57 inositol-1,4-bisphosphate 1-phosphatase
EC 3.1.3.58 sugar-terminal-phosphatase
EC 3.1.3.59 alkylacetylglycerophosphatase
EC 3.1.3.60 phosphoenolpyruvate phosphatase
EC 3.1.3.61 deleted
EC 3.1.3.62 multiple inositol-polyphosphate phosphatase
EC 3.1.3.63 2-carboxy-D-arabinitol-1-phosphatase
EC 3.1.3.64 phosphatidylinositol-3-phosphatase
EC 3.1.3.65 now with EC 3.1.3.64
EC 3.1.3.66 phosphatidylinositol-3,4-bisphosphate 4-phosphatase
EC 3.1.3.67 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase
EC 3.1.3.68 2-deoxyglucose-6-phosphatase
EC 3.1.3.69 glucosylglycerol 3-phosphatase
EC 3.1.3.70 mannosyl-3-phosphoglycerate phosphatase
EC 3.1.3.71 2-phosphosulfolactate phosphatase
EC 3.1.3.72 5-phytase
EC 3.1.3.73 adenosylcobalamin/α-ribazole phosphatase
EC 3.1.3.74 pyridoxal phosphatase
EC 3.1.3.75 phosphoethanolamine/phosphocholine phosphatase
EC 3.1.3.76 lipid-phosphate phosphatase
EC 3.1.3.77 acireductone synthase
EC 3.1.3.78 phosphatidylinositol-4,5-bisphosphate 4-phosphatase
EC 3.1.3.79 mannosylfructose-phosphate phosphatase
EC 3.1.3.80 2,3-bisphosphoglycerate 3-phosphatase
EC 3.1.3.81 diacylglycerol diphosphate phosphatase
EC 3.1.3.82 D-glycero-β-D-manno-heptose 1,7-bisphosphate 7-phosphatase
EC 3.1.3.83 D-glycero-α-D-manno-heptose 1,7-bisphosphate 7-phosphatase
EC 3.1.3.84 ADP-ribose 1"-phosphate phosphatase
EC 3.1.3.85 glucosyl-3-phosphoglycerate phosphatase
EC 3.1.3.86 phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase
EC 3.1.3.87 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate phosphatase
EC 3.1.3.88 5"-phosphoribostamycin phosphatase
EC 3.1.3.89 5'-deoxynucleotidase
EC 3.1.3.90 maltose 6'-phosphate phosphatase
EC 3.1.3.91 7-methylguanosine nucleotidase
EC 3.1.3.92 kanosamine-6-phosphate phosphatase
EC 3.1.3.93 L-galactose 1-phosphate phosphatase
EC 3.1.3.94 D-galactose 1-phosphate phosphatase
EC 3.1.3.95 phosphatidylinositol-3,5-bisphosphate 3-phosphatase
EC 3.1.3.96 pseudouridine 5'-phosphatase
EC 3.1.3.97 3',5'-nucleoside bisphosphate phosphatase
EC 3.1.3.98 now EC 3.6.1.68
EC 3.1.3.99 IMP-specific 5'-nucleotidase
EC 3.1.3.100 thiamine phosphate phosphatase
EC 3.1.3.101 validoxylamine A 7'-phosphate phosphatase
EC 3.1.3.102 FMN hydrolase
EC 3.1.3.103 3-deoxy-D-glycero-D-galacto-nononate 9-phosphatase
EC 3.1.3.104 5-amino-6-(5-phospho-D-ribitylamino)uracil phosphatase

EC 3.1.4 Phosphoric Diester Hydrolases

EC 3.1.4.1 phosphodiesterase I
EC 3.1.4.2 glycerophosphocholine phosphodiesterase
EC 3.1.4.3 phospholipase C
EC 3.1.4.4 phospholipase D
EC 3.1.4.5 now EC 3.1.21.1
EC 3.1.4.6 now EC 3.1.22.1
EC 3.1.4.7 now EC 3.1.31.1
EC 3.1.4.8 now EC 3.1.27.3
EC 3.1.4.9 now EC 3.1.30.2
EC 3.1.4.10 now EC 4.6.1.13
EC 3.1.4.11 phosphoinositide phospholipase C
EC 3.1.4.12 sphingomyelin phosphodiesterase
EC 3.1.4.13 serine-ethanolaminephosphate phosphodiesterase
EC 3.1.4.14 [acyl-carrier-protein] phosphodiesterase
EC 3.1.4.15 transferred now EC 2.7.7.89(17 September 2015)
EC 3.1.4.16 2',3'-cyclic-nucleotide 2'-phosphodiesterase
EC 3.1.4.17 3',5'-cyclic-nucleotide phosphodiesterase
EC 3.1.4.18 now EC 3.1.16.1
EC 3.1.4.19 now EC 3.1.13.3
EC 3.1.4.20 now EC 3.1.13.1
EC 3.1.4.21 now EC 3.1.30.1
EC 3.1.4.22 now EC 3.1.27.5
EC 3.1.4.23 now EC 3.1.27.1
EC 3.1.4.24 deleted
EC 3.1.4.25 now EC 3.1.11.1
EC 3.1.4.26 deleted
EC 3.1.4.27 now EC 3.1.11.2
EC 3.1.4.28 now EC 3.1.11.3
EC 3.1.4.29 deleted
EC 3.1.4.30 now EC 3.1.21.2
EC 3.1.4.31 now EC 3.1.11.4
EC 3.1.4.32 deleted
EC 3.1.4.33 deleted
EC 3.1.4.34 deleted
EC 3.1.4.35 3',5'-cyclic-GMP phosphodiesterase
EC 3.1.4.36 now with EC 3.1.4.43
EC 3.1.4.37 2',3'-cyclic-nucleotide 3'-phosphodiesterase
EC 3.1.4.38 glycerophosphocholine cholinephosphodiesterase
EC 3.1.4.39 alkylglycerophosphoethanolamine phosphodiesterase
EC 3.1.4.40 CMP-N-acylneuraminate phosphodiesterase
EC 3.1.4.41 sphingomyelin phosphodiesterase D
EC 3.1.4.42 glycerol-1,2-cyclic-phosphate 2-phosphodiesterase
EC 3.1.4.43 glycerophosphoinositol inositolphosphodiesterase
EC 3.1.4.44 glycerophosphoinositol glycerophosphodiesterase
EC 3.1.4.45 N-acetylglucosamine-1-phosphodiester α-N-acetylglucosaminidase
EC 3.1.4.46 glycerophosphodiester phosphodiesterase
EC 3.1.4.47 now EC 4.6.1.14
EC 3.1.4.48 dolichylphosphate-glucose phosphodiesterase
EC 3.1.4.49 dolichylphosphate-mannose phosphodiesterase
EC 3.1.4.50 glycosylphosphatidylinositol phospholipase D
EC 3.1.4.51 glucose-1-phospho-D-mannosylglycoprotein phosphodiesterase
EC 3.1.4.52 cyclic-guanylate-specific phosphodiesterase
EC 3.1.4.53 3',5'-cyclic-AMP phosphodiesterase
EC 3.1.4.54 N-acetylphosphatidylethanolamine-hydrolysing phospholipase D
EC 3.1.4.55 phosphoribosyl 1,2-cyclic phosphate phosphodiesterase
EC 3.1.4.56 7,8-dihydroneopterin 2',3'-cyclic phosphate phosphodiesterase
EC 3.1.4.57 phosphoribosyl 1,2-cyclic phosphate 1,2-diphosphodiesterase

EC 3.1.5 Triphosphoric Monoester Hydrolases

EC 3.1.5.1 dGTPase

EC 3.1.6 Sulfuric Ester Hydrolases

EC 3.1.6.1 arylsulfatase
EC 3.1.6.2 steryl-sulfatase
EC 3.1.6.3 glycosulfatase
EC 3.1.6.4 N-acetylgalactosamine-6-sulfatase
EC 3.1.6.5 deleted
EC 3.1.6.6 choline-sulfatase
EC 3.1.6.7 cellulose-polysulfatase
EC 3.1.6.8 cerebroside-sulfatase
EC 3.1.6.9 chondro-4-sulfatase
EC 3.1.6.10 chondro-6-sulfatase
EC 3.1.6.11 disulfoglucosamine-6-sulfatase
EC 3.1.6.12 N-acetylgalactosamine-4-sulfatase
EC 3.1.6.13 iduronate-2-sulfatase
EC 3.1.6.14 N-acetylglucosamine-6-sulfatase
EC 3.1.6.15 N-sulfoglucosamine-3-sulfatase
EC 3.1.6.16 monomethyl-sulfatase
EC 3.1.6.17 D-lactate-2-sulfatase
EC 3.1.6.18 glucuronate-2-sulfatase
EC 3.1.6.19 (R)-specific secondary-alkylsulfatase

EC 3.1.7 Diphosphoric Monoester Hydrolases

EC 3.1.7.1 prenyl-diphosphatase
EC 3.1.7.2 guanosine-3',5'-bis(diphosphate) 3'-diphosphatase
EC 3.1.7.3 monoterpenyl-diphosphatase
EC 3.1.7.4 deleted, now covered by EC 4.2.1.133 and EC 4.2.3.141
EC 3.1.7.5 geranylgeranyl diphosphate diphosphatase
EC 3.1.7.6 farnesyl diphosphatase
EC 3.1.7.7 drimenol cyclase
EC 3.1.7.8 tuberculosinol synthase
EC 3.1.7.9 isotuberculosinol synthase
EC 3.1.7.10 (13E)-labda-7,13-dien-15-ol synthase
EC 3.1.7.11 geranyl diphosphate diphosphatase

EC 3.1.8 Phosphoric Triester Hydrolases

EC 3.1.8.1 aryldialkylphosphatase
EC 3.1.8.2 diisopropyl-fluorophosphatase

EC 3.1.11 Exodeoxyribonucleases Producing 5'-Phosphomonoesters

EC 3.1.11.1 exodeoxyribonuclease I
EC 3.1.11.2 exodeoxyribonuclease III
EC 3.1.11.3 exodeoxyribonuclease (lambda-induced)
EC 3.1.11.4 exodeoxyribonuclease (phage SP3-induced)
EC 3.1.11.5 exodeoxyribonuclease V
EC 3.1.11.6 exodeoxyribonuclease VII
EC 3.1.11.7 adenosine-5'-diphospho-5'-[DNA] diphosphatase
EC 3.1.11.8 guanosine-5'-diphospho-5'-[DNA] diphosphatase

EC 3.1.12 Exodeoxyribonucleases Producing 3'-Phosphomonoesters

EC 3.1.12.1 5' to 3' exodeoxyribonuclease (nucleoside 3'-phosphate-forming)
EC 3.1.12.2 DNA-3'-diphospho-5'-guanosine diphosphatase

EC 3.1.13 Exoribonucleases Producing 5'-Phosphomonoesters

EC 3.1.13.1 exoribonuclease II
EC 3.1.13.2 exoribonuclease H
EC 3.1.13.3 oligonucleotidase
EC 3.1.13.4 poly(A)-specific ribonuclease
EC 3.1.13.5 ribonuclease D

EC 3.1.14 Exoribonucleases Producing 3'-Phosphomonoesters

EC 3.1.14.1 yeast ribonuclease

EC 3.1.15 Exonucleases Active with either Ribo- or Deoxyribonucleic Acids and Producing 5'-Phosphomonoesters

EC 3.1.15.1 venom exonuclease

EC 3.1.16 Exonucleases Active with either Ribo- or Deoxyribonucleic Acids and Producing 3'-Phosphomonoesters

EC 3.1.16.1 spleen exonuclease

EC 3.1.21 Endodeoxyribonucleases Producing 5'-Phosphomonoesters

EC 3.1.21.1 deoxyribonuclease I
EC 3.1.21.2 deoxyribonuclease IV
EC 3.1.21.3 type I site-specific deoxyribonuclease
EC 3.1.21.4 type II site-specific deoxyribonuclease
EC 3.1.21.5 type III site-specific deoxyribonuclease
EC 3.1.21.6 CC-preferring endodeoxyribonuclease
EC 3.1.21.7 deoxyribonuclease V

EC 3.1.21.8 T4 deoxyribonuclease II
EC 3.1.21.9 T4 deoxyribonuclease IV
EC 3.1.22 Endodeoxyribonucleases Producing 3'-Phosphomonoesters

EC 3.1.22.1 deoxyribonuclease II
EC 3.1.22.2 Aspergillus deoxyribonuclease K1
EC 3.1.22.3 now EC 3.1.21.7
EC 3.1.22.4 crossover junction endodeoxyribonuclease
EC 3.1.22.5 deoxyribonuclease X

EC 3.1.23 and EC 3.1.24 now EC 3.1.21.3, EC 3.1.21.4 and EC 3.1.21.5

EC 3.1.25 Site-Specific Endodeoxyribonucleases Specific for Altered Bases

EC 3.1.25.1 deoxyribonuclease (pyrimidine dimer)
EC 3.1.25.2 now EC 4.2.99.18

EC 3.1.26 Endoribonucleases Producing 5'-Phosphomonoesters

EC 3.1.26.1 Physarum polycephalum ribonuclease
EC 3.1.26.2 ribonuclease alpha
EC 3.1.26.3 ribonuclease III
EC 3.1.26.4 ribonuclease H
EC 3.1.26.5 ribonuclease P
EC 3.1.26.6 ribonuclease IV
EC 3.1.26.7 ribonuclease P4
EC 3.1.26.8 ribonuclease M5
EC 3.1.27.9 transferred now EC 4.6.1.16
EC 3.1.26.10 ribonuclease IX
EC 3.1.26.11 tRNase Z
EC 3.1.26.12 ribonuclease E
EC 3.1.26.13 retroviral ribonuclease H

EC 3.1.27 Endoribonucleases Producing 3'-Phosphomonoesters

EC 3.1.27.1 ribonuclease T2
EC 3.1.27.2 Bacillus subtilis ribonuclease
EC 3.1.27.3 ribonuclease T1
EC 3.1.27.4 ribonuclease U2
EC 3.1.27.5 pancreatic ribonuclease
EC 3.1.27.6 Enterobacter ribonuclease
EC 3.1.27.7 ribonuclease F
EC 3.1.27.8 ribonuclease V
EC 3.1.27.9 tRNA-intron endonuclease
EC 3.1.27.10 rRNA endonuclease

EC 3.1.30 Endoribonucleases Active with either Ribo- or Deoxyribonucleic Acids and Producing 5'-Phosphomonoesters

EC 3.1.30.1 Aspergillus nuclease S1
EC 3.1.30.2 Serratia marcescens nuclease

EC 3.1.31 Endoribonucleases Active with either Ribo- or Deoxyribonucleic Acids and Producing 3'-Phosphomonoesters

EC 3.1.31.1 micrococcal nuclease

EC 3.2 Glycosylases

EC 3.2.1 Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds

EC 3.2.1.1 α-amylase
EC 3.2.1.2 β-amylase
EC 3.2.1.3 glucan 1,4-α-glucosidase
EC 3.2.1.4 cellulase
EC 3.2.1.5 deleted
EC 3.2.1.6 endo-1,3(4)-β-glucanase
EC 3.2.1.7 inulinase
EC 3.2.1.8 endo-1,4-β-xylanase
EC 3.2.1.9 deleted
EC 3.2.1.10 oligo-1,6-glucosidase
EC 3.2.1.11 dextranase
EC 3.2.1.12 deleted, included in EC 3.2.1.54
EC 3.2.1.13 deleted, included in EC 3.2.1.54
EC 3.2.1.14 chitinase
EC 3.2.1.15 polygalacturonase
EC 3.2.1.16 deleted
EC 3.2.1.17 lysozyme
EC 3.2.1.18 exo-α-sialidase
EC 3.2.1.19 deleted
EC 3.2.1.20 α-glucosidase
EC 3.2.1.21 β-glucosidase
EC 3.2.1.22 α-galactosidase
EC 3.2.1.23 β-galactosidase
EC 3.2.1.24 α-mannosidase
EC 3.2.1.25 β-mannosidase
EC 3.2.1.26 β-fructofuranosidase
EC 3.2.1.27 deleted
EC 3.2.1.28 α,α-trehalase
EC 3.2.1.29 deleted, included in EC 3.2.1.52
EC 3.2.1.30 deleted, included in EC 3.2.1.52
EC 3.2.1.31 β-glucuronidase
EC 3.2.1.32 endo-1,3-β-xylanase
EC 3.2.1.33 amylo-1,6-glucosidase
EC 3.2.1.34 deleted, included in EC 3.2.1.35
EC 3.2.1.35 hyaluronoglucosaminidase
EC 3.2.1.36 hyaluronoglucuronidase
EC 3.2.1.37 xylan 1,4-β-xylosidase
EC 3.2.1.38 β-D-fucosidase
EC 3.2.1.39 glucan endo-1,3-β-D-glucosidase
EC 3.2.1.40 α-L-rhamnosidase
EC 3.2.1.41 pullulanase
EC 3.2.1.42 GDP-glucosidase
EC 3.2.1.43 β-L-rhamnosidase
EC 3.2.1.44 fucoidanase
EC 3.2.1.45 glucosylceramidase
EC 3.2.1.46 galactosylceramidase
EC 3.2.1.47 galactosylgalactosylglucosylceramidase
EC 3.2.1.48 sucrose α-glucosidase
EC 3.2.1.49 α-N-acetylgalactosaminidase
EC 3.2.1.50 α-N-acetylglucosaminidase
EC 3.2.1.51 α-L-fucosidase
EC 3.2.1.52 β-N-acetylhexosaminidase
EC 3.2.1.53 β-N-acetylgalactosaminidase
EC 3.2.1.54 cyclomaltodextrinase
EC 3.2.1.55 non-reducing end α-L-arabinofuranosidase
EC 3.2.1.56 glucuronosyl-disulfoglucosamine glucuronidase
EC 3.2.1.57 isopullulanase
EC 3.2.1.58 glucan 1,3-β-glucosidase
EC 3.2.1.59 glucan endo-1,3-α-glucosidase
EC 3.2.1.60 glucan 1,4-α-maltotetraohydrolase
EC 3.2.1.61 mycodextranase
EC 3.2.1.62 glycosylceramidase
EC 3.2.1.63 1,2-α-L-fucosidase
EC 3.2.1.64 2,6-β-fructan 6-levanbiohydrolase
EC 3.2.1.65 levanase
EC 3.2.1.66 quercitrinase
EC 3.2.1.67 galacturan 1,4-α-galacturonidase
EC 3.2.1.68 isoamylase
EC 3.2.1.69 deleted, included in EC 3.2.1.41
EC 3.2.1.70 glucan 1,6-α-glucosidase
EC 3.2.1.71 glucan endo-1,2-β-glucosidase
EC 3.2.1.72 xylan 1,3-β-xylosidase
EC 3.2.1.73 licheninase
EC 3.2.1.74 glucan 1,4-β-glucosidase
EC 3.2.1.75 glucan endo-1,6-β-glucosidase
EC 3.2.1.76 L-iduronidase
EC 3.2.1.77 mannan 1,2-(1,3)-α-mannosidase
EC 3.2.1.78 mannan endo-1,4-β-mannosidase
EC 3.2.1.79 deleted, included in EC 3.2.1.55
EC 3.2.1.80 fructan β-fructosidase
EC 3.2.1.81 β-agarase
EC 3.2.1.82 exo-poly-α-galacturonosidase
EC 3.2.1.83 κ-carrageenase
EC 3.2.1.84 glucan 1,3-α-glucosidase
EC 3.2.1.85 6-phospho-β-galactosidase
EC 3.2.1.86 6-phospho-β-glucosidase
EC 3.2.1.87 capsular-polysaccharide endo-1,3-α-galactosidase
EC 3.2.1.88 non-reducing end β-L-arabinopyranosidase
EC 3.2.1.89 arabinogalactan endo-β-1,4-galactanase
EC 3.2.1.90 deleted, not sufficiently characterised.
EC 3.2.1.91 cellulose 1,4-β-cellobiosidase (non-reducing end)
EC 3.2.1.92 peptidoglycan β-N-acetylmuramidase
EC 3.2.1.93 α,α-phosphotrehalase
EC 3.2.1.94 glucan 1,6-α-isomaltosidase
EC 3.2.1.95 dextran 1,6-α-isomaltotriosidase
EC 3.2.1.96 mannosyl-glycoprotein endo-β-N-acetylglucosaminidase
EC 3.2.1.97 endo-α-N-acetylgalactosaminidase
EC 3.2.1.98 glucan 1,4-α-maltohexaosidase
EC 3.2.1.99 arabinan endo-1,5-α-L-arabinanase
EC 3.2.1.100 mannan 1,4-mannobiosidase
EC 3.2.1.101 mannan endo-1,6-α-mannosidase
EC 3.2.1.102 blood-group-substance endo-1,4-β-galactosidase
EC 3.2.1.103 keratan-sulfate endo-1,4-β-galactosidase
EC 3.2.1.104 steryl-β-glucosidase
EC 3.2.1.105 strictosidine β-glucosidase
EC 3.2.1.106 mannosyl-oligosaccharide glucosidase
EC 3.2.1.107 protein-glucosylgalactosylhydroxylysine glucosidase
EC 3.2.1.108 lactase
EC 3.2.1.109 endogalactosaminidase
EC 3.2.1.110 deleted identical to EC 3.2.1.97
EC 3.2.1.111 1,3-α-L-fucosidase
EC 3.2.1.112 2-deoxyglucosidase
EC 3.2.1.113 mannosyl-oligosaccharide 1,2-α-mannosidase
EC 3.2.1.114 mannosyl-oligosaccharide 1,3-1,6-α-mannosidase
EC 3.2.1.115 branched-dextran exo-1,2-α-glucosidase
EC 3.2.1.116 glucan 1,4-α-maltotriohydrolase
EC 3.2.1.117 amygdalin β-glucosidase
EC 3.2.1.118 prunasin β-glucosidase
EC 3.2.1.119 vicianin β-glucosidase
EC 3.2.1.120 oligoxyloglucan β-glycosidase
EC 3.2.1.121 polymannuronate hydrolase
EC 3.2.1.122 maltose-6'-phosphate glucosidase
EC 3.2.1.123 endoglycosylceramidase
EC 3.2.1.124 3-deoxy-2-octulosonidase
EC 3.2.1.125 raucaffricine β-glucosidase
EC 3.2.1.126 coniferin β-glucosidase
EC 3.2.1.127 1,6-α-L-fucosidase
EC 3.2.1.128 glycyrrhizinate β-glucuronidase
EC 3.2.1.129 endo-α-sialidase
EC 3.2.1.130 glycoprotein endo-α-1,2-mannosidase
EC 3.2.1.131 xylan α-1,2-glucuronosidase
EC 3.2.1.132 chitosanase
EC 3.2.1.133 glucan 1,4-α-maltohydrolase
EC 3.2.1.134 difructose-anhydride synthase
EC 3.2.1.135 neopullulanase
EC 3.2.1.136 glucuronoarabinoxylan endo-1,4-β-xylanase
EC 3.2.1.137 mannan exo-1,2-1,6-α-mannosidase
EC 3.2.1.138 now EC 4.2.2.15
EC 3.2.1.139 α-glucuronidase
EC 3.2.1.140 lacto-N-biosidase
EC 3.2.1.141 4-α-D-{(1→4)-α-D-glucano}trehalose trehalohydrolase
EC 3.2.1.142 limit dextrinase
EC 3.2.1.143 poly(ADP-ribose) glycohydrolase
EC 3.2.1.144 3-deoxyoctulosonase
EC 3.2.1.145 galactan 1,3-β-galactosidase
EC 3.2.1.146 β-galactofuranosidase
EC 3.2.1.147 thioglucosidase
EC 3.2.1.148 now EC 4.4.1.21
EC 3.2.1.149 β-primeverosidase
EC 3.2.1.150 oligoxyloglucan reducing-end-specific cellobiohydrolase
EC 3.2.1.151 xyloglucan-specific endo-β-1,4-glucanase
EC 3.2.1.152 mannosylglycoprotein endo-β-mannosidase
EC 3.2.1.153 fructan β-(2,1)-fructosidase
EC 3.2.1.154 fructan β-(2,6)-fructosidase
EC 3.2.1.155 xyloglucan-specific exo-β-1,4-glucanase
EC 3.2.1.156 oligosaccharide reducing-end xylanase
EC 3.2.1.157 ι-carrageenase
EC 3.2.1.158 α-agarase
EC 3.2.1.159 α-neoagaro-oligosaccharide hydrolase
EC 3.2.1.160 deleted, identical to EC 3.2.1.155
EC 3.2.1.161 β-apiosyl-β-glucosidase
EC 3.2.1.162 λ-carrageenase
EC 3.2.1.163 1,6-α-D-mannosidase
EC 3.2.1.164 galactan endo-1,6-β-galactosidase
EC 3.2.1.165 exo-1,4-β-D-glucosaminidase
EC 3.2.1.166 heparanase
EC 3.2.1.167 baicalin-β-D-glucuronidase
EC 3.2.1.168 hesperidin 6-O-α-L-rhamnosyl-β-D-glucosidase
EC 3.2.1.169 protein O-GlcNAcase
EC 3.2.1.170 mannosylglycerate hydrolase
EC 3.2.1.171 rhamnogalacturonan hydrolase
EC 3.2.1.172 unsaturated rhamnogalacturonyl hydrolase
EC 3.2.1.173 rhamnogalacturonan galacturonohydrolase
EC 3.2.1.174 rhamnogalacturonan rhamnohydrolase
EC 3.2.1.175 β-D-glucopyranosyl abscisate β-glucosidase
EC 3.2.1.176 cellulose 1,4-β-cellobiosidase (reducing end)
EC 3.2.1.177 α-D-xyloside xylohydrolase
EC 3.2.1.178 β-porphyranase
EC 3.2.1.179 gellan tetrasaccharide unsaturated glucuronyl hydrolase
EC 3.2.1.180 unsaturated chondroitin disaccharide hydrolase
EC 3.2.1.181 galactan endo-β-1,3-galactanase
EC 3.2.1.182 4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside β-D-glucosidase
EC 3.2.1.183 UDP-N-acetylglucosamine 2-epimerase (hydrolysing)
EC 3.2.1.184 UDP-N,N'-diacetylbacillosamine 2-epimerase (hydrolysing)
EC 3.2.1.185 non-reducing end β-L-arabinofuranosidase
EC 3.2.1.186 protodioscin 26-O-β-D-glucosidase
EC 3.2.1.187 (Ara-f)3-Hyp β-L-arabinobiosidase
EC 3.2.1.188 avenacosidase
EC 3.2.1.189 dioscin glycosidase (diosgenin-forming)
EC 3.2.1.190 dioscin glycosidase (3-O-β-D-Glc-diosgenin-forming)
EC 3.2.1.191 ginsenosidase type III
EC 3.2.1.192 ginsenoside Rb1 β-glucosidase
EC 3.2.1.193 ginsenosidase type I
EC 3.2.1.194 ginsenosidase type IV
EC 3.2.1.195 20-O-multi-glycoside ginsenosidase
EC 3.2.1.196 limit dextrin α-1,6-maltotetraose-hydrolase
EC 3.2.1.197 β-1,2-mannosidase
EC 3.2.1.198 α-mannan endo-1,2-α-mannanase
EC 3.2.1.199 sulfoquinovosidase
EC 3.2.1.200 exo-chitinase (non-reducing end)
EC 3.2.1.201 exo-chitinase (reducing end)
EC 3.2.1.202 endo-chitodextinase
EC 3.2.1.203 carboxymethylcellulase

EC 3.2.2 Hydrolysing N-Glycosyl Compounds

EC 3.2.2.1 purine nucleosidase
EC 3.2.2.2 inosine nucleosidase
EC 3.2.2.3 uridine nucleosidase
EC 3.2.2.4 AMP nucleosidase
EC 3.2.2.5 NAD+ glycohydrolase
EC 3.2.2.6 ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase
EC 3.2.2.7 adenosine nucleosidase
EC 3.2.2.8 ribosylpyrimidine nucleosidase
EC 3.2.2.9 adenosylhomocysteine nucleosidase
EC 3.2.2.10 pyrimidine-5'-nucleotide nucleosidase
EC 3.2.2.11 β-aspartyl-N-acetylglucosaminidase
EC 3.2.2.12 inosinate nucleosidase
EC 3.2.2.13 1-methyladenosine nucleosidase
EC 3.2.2.14 NMN nucleosidase
EC 3.2.2.15 DNA-deoxyinosine glycosylase
EC 3.2.2.16 methylthioadenosine nucleosidase
EC 3.2.2.17 deoxyribodipyrimidine endonucleosidase
EC 3.2.2.18 deleted, included in EC 3.5.1.52
EC 3.2.2.19 ADP-ribosylarginine hydrolase
EC 3.2.2.20 DNA-3-methyladenine glycosylase I
EC 3.2.2.21 DNA-3-methyladenine glycosylase II
EC 3.2.2.22 rRNA N-glycosylase
EC 3.2.2.23 DNA-formamidopyrimidine glycosylase
EC 3.2.2.24 ADP-ribosyl-[dinitrogen reductase] hydrolase
EC 3.2.2.25 N-methyl nucleosidase
EC 3.2.2.26 futalosine hydrolase
EC 3.2.2.27 uracil-DNA glycosylase
EC 3.2.2.28 double-stranded uracil-DNA glycosylase
EC 3.2.2.29 thymine-DNA glycosylase
EC 3.2.2.30 aminodeoxyfutalosine nucleosidase

EC 3.2.3 Hydrolysing S-Glycosyl Compounds (discontinued)

EC 3.2.3.1 now EC 3.2.1.147

EC 3.3 Acting on Ether Bonds

EC 3.3.1 Thioether and Trialkylsulfonium Hydrolases

EC 3.3.1.1 adenosylhomocysteinase
EC 3.3.1.2 adenosylmethionine hydrolase
EC 3.3.1.3 now EC 3.2.1.148

EC 3.3.2 Ether Hydrolases

EC 3.3.2.1 isochorismatase
EC 3.3.2.2 lysoplasmalogenase
EC 3.3.2.3 now EC 3.3.2.9 and EC 3.3.2.10
EC 3.3.2.4 trans-epoxysuccinate hydrolase
EC 3.3.2.5 transferred now covered by EC 3.3.2.2
EC 3.3.2.6 leukotriene-A4 hydrolase
EC 3.3.2.7 hepoxilin-epoxide hydrolase
EC 3.3.2.8 limonene-1,2-epoxide hydrolase
EC 3.3.2.9 microsomal epoxide hydrolase
EC 3.3.2.10 soluble epoxide hydrolase
EC 3.3.2.11 cholesterol-5,6-oxide hydrolase
EC 3.3.2.12 oxepin-CoA hydrolase
EC 3.3.2.13 chorismatase
EC 3.3.2.14 2,4-dinitroanisole O-demethylase
EC 3.3.2.15 trans-2,3-dihydro-3-hydroxyanthranilic acid synthase


Continued with Contents for EC 3.4 to EC 3.12
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