IUBMB Enzyme Nomenclature

EC 4.1.1.25

Accepted name: tyrosine decarboxylase

Reaction: L-tyrosine = tyramine + CO2

Other name(s): L-tyrosine decarboxylase; L-(–)-tyrosine apodecarboxylase; L-tyrosine carboxy-lyase

Systematic name: L-tyrosine carboxy-lyase (tyramine-forming)

Comments: A pyridoxal-phosphate protein. The bacterial enzyme also acts on 3-hydroxytyrosine and, more slowly, on 3-hydroxyphenylalanine.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, PDB, CAS registry number: 9002-09-9

References:

1. McGilvery, R.W. and Cohen, P.P. The decarboxylation of L-phenylalanine by Streptococcus faecalis R. J. Biol. Chem. 174 (1948) 813-816.

[EC 4.1.1.25 created 1961]


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