IUBMB Enzyme Nomenclature


Accepted name: tartronate-semialdehyde synthase

Reaction: 2 glyoxylate = 2-hydroxy-3-oxopropanoate + CO2

Glossary: 2-hydroxy-3-oxopropanoate = tartronate semialdehyde

Other name(s): tartronate semialdehyde carboxylase; glyoxylate carbo-ligase; glyoxylic carbo-ligase; hydroxymalonic semialdehyde carboxylase; tartronic semialdehyde carboxylase; glyoxalate carboligase; glyoxylate carboxy-lyase (dimerizing)

Systematic name: glyoxylate carboxy-lyase (dimerizing; tartronate-semialdehyde-forming)

Comments: A flavoprotein.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, PDB, CAS registry number: 9027-24-1


1. Gupta, N.K. and Vennesland, B. Glyoxylate carboligase of Escherichia coli: a flavoprotein. J. Biol. Chem. 239 (1964) 3787-3789.

2. Krakow, G. and Barkulis, S.S. Conversion of glyoxylate to hydroxypyruvate by extracts of Escherichia coli. Biochim. Biophys. Acta 21 (1956) 593-594.

[EC created 1972]

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