IUBMB Enzyme Nomenclature

EC 4.1.1.50

Accepted name: adenosylmethionine decarboxylase

Reaction: S-adenosyl-L-methionine = S-adenosyl 3-(methylthio)propylamine + CO2

For diagram of reaction click here or click here.

Other name(s): S-adenosylmethionine decarboxylase; S-adenosyl-L-methionine decarboxylase; S-adenosyl-L-methionine carboxy-lyase

Systematic name: S-adenosyl-L-methionine carboxy-lyase [(5-deoxy-5-adenosyl)(3-aminopropyl)methylsulfonium-salt-forming]

Comments: The Escherichia coli enzyme contains a pyruvoyl group.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, PDB, CAS registry number: 9036-20-8

References:

1. Anton, D.A.and Kutny, R. Escherichia coli S-adenosylmethionine decarboxylase. Subunit structure, reductive amination, and NH2-terminal sequences. J. Biol. Chem. 262 (1987) 2817-2822. [PMID: 3546296]

2. Tabor, C.W. Adenosylmethionine decarboxylase.Methods Enzymol. 5 (1962) 756-760.

[EC 4.1.1.50 created 1972]


Return to EC 4.1.1 home page
Return to EC 4.3 home page
Return to EC 4 home page
Return to Enzymes home page
Return to IUBMB Biochemical Nomenclature home page