Reaction: cis-aconitate = itaconate + CO2
Glossary: itaconic acid = 2-methylenesuccinic acid
cis-Aconitate = (Z)-prop-1-ene-1,2,3-tricarboxylate
Other name(s): cis-aconitic decarboxylase; CAD; cis-aconitate carboxy-lyase
Systematic name: cis-aconitate carboxy-lyase (itaconate-forming)
Links to other databases: BRENDA, EXPASY, KEGG, CAS registry number: 9025-01-8
References:
1. Bentley, R. and Thiessen, C.P. Biosynthesis of itaconic acid in Aspergillus terreus. III. The properties and reaction mechanism of cis-aconitic acid decarboxylase. J. Biol. Chem. 226 (1957) 703-720.