IUBMB Enzyme Nomenclature


Accepted name: acetylenedicarboxylate decarboxylase

Reaction: acetylenedicarboxylate + H2O = pyruvate + CO2

Other name(s): acetylenedicarboxylate hydratase; acetylenedicarboxylate hydrase; cetylenedicarboxylate carboxy-lyase

Systematic name: acetylenedicarboxylate carboxy-lyase (pyruvate-forming)

Comments: The mechanism appears to involve hydration of the acetylene and decarboxylation of the oxaloacetic acid formed, although free oxaloacetate is not an intermediate. It is thus analogous to EC (acetylenecarboxylate hydratase) in its mechanism. Formerly EC

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 72561-10-5


1. Yamada, E.W. and Jakoby, W.B. Enzymatic utilization of acetylenic compounds. I. An enzyme converting acetylenedicarboxylic acid to pyruvate. J. Biol. Chem. 233 (1958) 706-711.

[EC created 1978 as EC, transferred 2000 to EC]

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