Reaction: malonyl-CoA = acetyl-CoA + CO2
Other name(s): malonyl coenzyme A decarboxylase; malonyl-CoA carboxy-lyase
Systematic name: malonyl-CoA carboxy-lyase (acetyl-CoA-forming)
Comments: Specific for malonyl-CoA. The enzyme from Pseudomonas ovalis also catalyses the reaction of EC 22.214.171.124 malonate CoA-transferase.
Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, PDB, CAS registry number: 9024-99-1
1. Buckner, J.S., Kolattudy, P.E. and Poulose, A.J. Purification and properties of malonyl-coenzyme A decarboxylase, a regulatory enzyme from the uropygial gland of goose. Arch. Biochem. Biophys. 177 (1976) 539-551. [PMID: 827976]
2. Takamura, Y. and Kitayama, Y. Purification and some properties of malonate decarboxylase from Pseudomonas ovalis - an oligomeric enzyme with bifunctional properties. Biochem. Int. 3 (1981) 483-491.