IUBMB Enzyme Nomenclature


Accepted name: malonyl-CoA decarboxylase

Reaction: malonyl-CoA = acetyl-CoA + CO2

Other name(s): malonyl coenzyme A decarboxylase; malonyl-CoA carboxy-lyase

Systematic name: malonyl-CoA carboxy-lyase (acetyl-CoA-forming)

Comments: Specific for malonyl-CoA. The enzyme from Pseudomonas ovalis also catalyses the reaction of EC malonate CoA-transferase.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, PDB, CAS registry number: 9024-99-1


1. Buckner, J.S., Kolattudy, P.E. and Poulose, A.J. Purification and properties of malonyl-coenzyme A decarboxylase, a regulatory enzyme from the uropygial gland of goose. Arch. Biochem. Biophys. 177 (1976) 539-551. [PMID: 827976]

2. Takamura, Y. and Kitayama, Y. Purification and some properties of malonate decarboxylase from Pseudomonas ovalis - an oligomeric enzyme with bifunctional properties. Biochem. Int. 3 (1981) 483-491.

[EC created 1961, deleted 1972, reinstated 1978]

Return to EC 4.1.1 home page
Return to EC 4.3 home page
Return to EC 4 home page
Return to Enzymes home page
Return to IUBMB Biochemical Nomenclature home page