IUBMB Enzyme Nomenclature


Accepted name: tagatose-bisphosphate aldolase

Reaction: D-tagatose 1,6-bisphosphate = glycerone phosphate + D-glyceraldehyde 3-phosphate

Other name(s): D-tagatose-1,6-bisphosphate triosephosphate lyase

Systematic name: D-tagatose-1,6-bisphosphate triosephosphate lyase (glycerone-phosphate-forming)

Comments: enzyme activity is stimulated by certain divalent cations. It is involved in the tagatose 6-phosphate pathway of lactose catabolism in bacteria.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, PDB, CAS registry number: 39433-95-9


1. Anderson, R.L., Markwell, J.P. D-Tagatose-1,6-bisphosphate aldolase (Class II) from Klebsiella pneumoniae. Methods Enzymol. 90 (1982) 323-324.

2. Van Rooijen, R.J., Van Schalkwijk, S., De Vos, W.M. Molecular cloning, characterization, and nucleotide sequence of the tagatose 6-phosphate pathway gene cluster of the lactose operon of Lactococcus lactis. J. Biol. Chem. 266 (1991) 7176-7181. [PMID: 1901863]

[EC created 1999]

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