IUBMB Enzyme Nomenclature


Accepted name: fumarate hydratase

Reaction: (S)-malate = fumarate + H2O

For diagram of reaction click here (another example or another example).

Other name(s): fumarase; L-malate hydro-lyase; (S)-malate hydro-lyase

Systematic name: (S)-malate hydro-lyase (fumarate-forming)

Links to other databases: BRENDA, EXPASY, GTD, KEGG, Metacyc, PDB, CAS registry number: 9032-88-6


1. Alberty, R.A. Fumarase, in Boyer, P.D., Lardy, H. and Myrbäck, K. (Eds.), The Enzymes, 2nd edn., vol. 5, Academic Press, New York, 1961, pp. 531-544.

2. Kanarek, L. and Hill, R.L. The preparation and characterization of fumarase from swine heart muscle. J. Biol. Chem. 239 (1964) 4202-4206. [PMID: 14247669]

[EC created 1961]

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