IUBMB Enzyme Nomenclature

EC 4.2.1.28

Accepted name: propanediol dehydratase

Reaction: propane-1,2-diol = propanal + H2O

Other name(s): meso-2,3-butanediol dehydrase; diol dehydratase; DL-1,2-propanediol hydro-lyase; diol dehydrase; adenosylcobalamin-dependent diol dehydratase; propanediol dehydrase; coenzyme B12-dependent diol dehydrase; 1,2-propanediol dehydratase; dioldehydratase; propane-1,2-diol hydro-lyase

Systematic name: propane-1,2-diol hydro-lyase (propanal-forming)

Comments: Requires a cobamide coenzyme. Also dehydrates ethylene glycol to acetaldehyde.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, PDB, CAS registry number: 9026-90-8

References:

1. Abeles, R.H. and Lee, H.A., Jr. An intramolecular oxidation-reduction requiring a cobamide coenzyme. J. Biol. Chem. 236 (1961) 2347-2350. [PMID: 13680987]

2. Forage, R.G. and Foster, M.A. Glycerol fermentation in Klebsiella pneumoniae: functions of the coenzyme B12-dependent glycerol and diol dehydratases. J. Bacteriol. 149 (1982) 413-419. [PMID: 7035429]

3. Lee, H.A. and Abeles, R.H. Purification and properties of dioldehydrase, and enzyme requiring a cobamide coenzyme. J. Biol. Chem. 238 (1963) 2367-2373. [PMID: 13929077]

[EC 4.2.1.28 created 1965]


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