IUBMB Enzyme Nomenclature


Accepted name: (S)-2-methylmalate dehydratase

Reaction: (S)-2-methylmalate = 2-methylfumarate + H2O

Other name(s): mesaconate hydratase; (+)-citramalate hydro-lyase; L-citramalate hydrolase; citramalate dehydratase; (+)-citramalic hydro-lyase; mesaconate mesaconase; mesaconase; (S)-2-methylmalate hydro-lyase

Systematic name: (S)-2-methylmalate hydro-lyase (2-methylfumarate-forming)

Comments: Also hydrates fumarate to (S)-malate.

Links to other databases: BRENDA, EXPASY, GTD, KEGG, Metacyc, CAS registry number: 9027-94-5


1. Blair, A.H. and Barker, H.A. Assay and purification of (+)-citramalate hydro-lyase components from Clostridium tetanomorphum. J. Biol. Chem. 241 (1966) 400-408. [PMID: 5903732]

2. Wang, C.C. and Barker, H.A. Purification and properties of L-citramalate hydrolyase. J. Biol. Chem. 244 (1969) 2516-2526. [PMID: 5769987]

[EC created 1972]

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