IUBMB Enzyme Nomenclature

EC 4.2.1.39

Accepted name: gluconate dehydratase

Reaction: D-gluconate = 2-dehydro-3-deoxy-D-gluconate + H2O

For diagram of reaction click here.

Other name(s): D-gluconate dehydratase; D-gluconate hydro-lyase

Systematic name: D-gluconate hydro-lyase (2-dehydro-3-deoxy-D-gluconate-forming)

Comments: The enzyme shows no activity with D-galactonate [2]. cf. EC 4.2.1.140, gluconate/galactonate dehydratase.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 37290-75-8

References:

1. Andreesen, J.R. and Gottschalk, G. The occurrence of a modified Entner-Doudoroff pathway in Clostridium aceticum. Arch. Mikrobiol. 69 (1969) 160-170. [PMID: 5383859]

2. Bender, R. and Gottschalk, G. Purification and properties of D-gluconate dehydratase from Clostridium pasteurianum. Eur. J. Biochem. 40 (1973) 309-321. [PMID: 4772682]

[EC 4.2.1.39 created 1972]


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