IUBMB Enzyme Nomenclature

EC 4.2.1.52

Accepted name: dihydrodipicolinate synthase

Reaction: L-aspartate 4-semialdehyde + pyruvate = (S)-2,3-dihydropyridine-2,6-dicarboxylate + 2 H2O

For diagram click here.

Glossary: dihydrodipicolinate = (S)-2,3-dihydropyridine-2,6-dicarboxylate

Other name(s): dihydropicolinate synthetase; dihydrodipicolinic acid synthase; L-aspartate-4-semialdehyde hydro-lyase (adding pyruvate and cyclizing)

Systematic name: L-aspartate-4-semialdehyde hydro-lyase [adding pyruvate and cyclizing; (S)-2,3-dihydropyridine-2,6-dicarboxylate-forming]

Links to other databases: BRENDA, EXPASY, KEGG, PDB, CAS registry number: 9055-59-8

References:

1. Shedlarski, J.G. and Gilvarg, C. The pyruvate-aspartic semialdehyde condensing enzyme of Escherichia coli. J. Biol. Chem. 245 (1970) 1362-1373. [PMID: 4910051]

2. Yugari, Y. and Gilvarg, C. The condensation step in diaminopimelate synthesis. J. Biol. Chem. 240 (1965) 4710-4716. [PMID: 5321309]

[EC 4.2.1.52 created 1972]


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