IUBMB Enzyme Nomenclature

EC 4.2.1.58

Accepted name: crotonoyl-[acyl-carrier-protein] hydratase

Reaction: a (3R)-3-hydroxybutanoyl-[acyl-carrier protein] = a but-2-enoyl-[acyl-carrier protein] + H2O

Other name(s): β-hydroxybutyryl acyl carrier protein dehydrase; β-hydroxybutyryl acyl carrier protein (ACP) dehydrase; β-hydroxybutyryl acyl carrier protein dehydrase; enoyl acyl carrier protein hydrase; crotonyl acyl carrier protein hydratase; 3-hydroxybutyryl acyl carrier protein dehydratase; β-hydroxybutyryl acyl carrier protein dehydrase; (3R)-3-hydroxybutanoyl-[acyl-carrier-protein] hydro-lyase

Systematic name: (3R)-3-hydroxybutanoyl-[acyl-carrier protein] hydro-lyase (but-2-enoyl-[acyl-carrier protein]-forming)

Comments: Is specific for short chain-length 3-hydroxyacyl-[acyl-carrier protein] derivatives (C4 to C8).

Links to other databases: BRENDA, EXPASY, GTD, KEGG, CAS registry number: 9030-78-8

References:

1. Majerus, P.W., Alberts, A.W. and Vagelos, P.R. Acyl carrier protein. 3. An enoyl hydrase specific for acyl carrier protein thioesters. J. Biol. Chem. 240 (1965) 618-621. [PMID: 14275113]

2. Mizugaki, M., Weeks, G., Toomey, R.E. and Wakil, S.J. Studies on the mechanism of fatty acid synthesis. XX. Preparation and general properties of β-hydroxybutyryl acyl carrier protein dehydrase. J. Biol. Chem. 243 (1968 )3661-3670. [PMID: 5658542]

[EC 4.2.1.58 created 1972]


Return to EC 4.2.1 home page
Return to EC 4.2 home page
Return to EC 4 home page
Return to Enzymes home page
Return to IUBMB Biochemical Nomenclature home page