IUBMB Enzyme Nomenclature

EC 4.2.1.77

Accepted name: trans-L-3-hydroxyproline dehydratase

Reaction: trans-L-3-hydroxyproline = Δ1-pyrroline 2-carboxylate + H2O

Other name(s): trans-L-3-hydroxyproline hydro-lyase

Systematic name: trans-L-3-hydroxyproline hydro-lyase (Δ1-pyrroline-2-carboxylate-forming)

Comments: Highly specific. 2,3-Dehydroproline is an intermediate.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number:

References:

1. Ramaswamy, S.G. Conversion of 3-hydroxyproline to proline in the rat requires reduced pyridine-nucleotides. Fed. Proc. 42 (1983) 2232 only.

[EC 4.2.1.77 created 1984]


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