IUBMB Enzyme Nomenclature


Accepted name: (+)-δ-cadinene synthase

Reaction: (2E,6E)-farnesyl diphosphate = (+)-δ-cadinene + diphosphate

For reaction pathway click here.

Other name(s): 2-trans,6-trans-farnesyl-diphosphate diphosphate-lyase (cyclizing, (+)-δ-cadinene-forming)

Systematic name: (2E,6E)-farnesyl-diphosphate diphosphate-lyase (cyclizing, (+)-δ-cadinene-forming)

Comments: the sesquiterpenoid (+)-δ-cadinene is an intermediate in phytoalexin biosynthesis. Mg2+ is required for activity.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, PDB, CAS registry number: 166800-09-5


1. Chen, X.-Y., Chen, Y., Heinstein, P., Davisson, V.J. Cloning, expression and characterization of (+)-δ-cadinene synthase: a catalyst for cotton phytoalexin biosynthesis. Arch. Biochem. Biophys. 324 (1995) 255-266. [PMID: 8554317]

2. Davis, E.M., Tsuji, J., Davis, G.D., Pierce, M.L., Essenberg, M. Purification of (+)-δ-cadinene synthase, a sesquiterpene cyclase from bacteria-inoculated cotton foliar tissue. Phytochemistry 41 (1996) 1047-1055.

3. Davis, G.D., Essenberg, M. (+)-δ-Cadinene is a product of sesquiterpene cyclase activity in cotton. Phytochemistry 39 (1995) 553-567.

[EC created 1999 as EC, transferred 2000 to EC]

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