IUBMB Enzyme Nomenclature


Accepted name: tetraprenyl-β-curcumene synthase

Reaction: all-trans-heptaprenyl diphosphate = tetraprenyl-β-curcumene + diphosphate

For diagram of reaction click here.

Other name(s): ytpB (gene name)

Systematic name: all-trans-heptaprenyl-diphosphate diphosphate-lyase (cyclizing, tetraprenyl-β-curcumene-forming)

Comments: Isolated from Bacillus subtilis. This sesquarterpene is present in a number of Bacillus species.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number:


1. Sato, T., Yoshida, S., Hoshino, H., Tanno, M., Nakajima, M. and Hoshino, T. Sesquarterpenes (C35 terpenes) biosynthesized via the cyclization of a linear C35 isoprenoid by a tetraprenyl-β-curcumene synthase and a tetraprenyl-β-curcumene cyclase: identification of a new terpene cyclase. J. Am. Chem. Soc. 133 (2011) 9734-9737. [PMID: 21627333]

[EC created 2012]

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