IUBMB Enzyme Nomenclature

EC 4.2.3.15

Accepted name: myrcene synthase

Reaction: geranyl diphosphate = myrcene + diphosphate

For reaction pathway click here.

Glossary entries:
myrcene: a monoterpenoid

Systematic name: geranyl-diphosphate diphosphate-lyase (myrcene-forming)

Comments: A recombinant enzyme (also known as a monoterpene synthase or cyclase) from the grand fir (Abies grandis) requires Mn2+ and K+ for activity. Mg2+ is essentially ineffective as the divalent metal ion cofactor.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 197462-59-2

References:

1. Bohlmann, J., Steele, C.L. and Croteau, R. Monoterpene synthases from grand fir (Abies grandis). cDNA isolation, characterization, and functional expression of myrcene synthase, (–}-(4S)-limonene synthase, and (–}-(1S,5S)-pinene synthase. J. Biol. Chem. 272 (1997) 21784-21792. [PMID: 9268308]

[EC 4.2.3.15 created 2000 as EC 4.1.99.9, transferred 2000 to EC 4.2.3.15]


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