Reaction: L-dopa + 2 NADH = 3,4-dihydroxyphenylpropanoate + 2 NAD+ + NH3
Glossary: L-dopa = 3,4-dihydroxy-L-phenylalanine
Other name(s): reductive deaminase; DOPA-reductive deaminase; DOPARDA
Systematic name: 3,4-dihydroxy-L-phenylalanine ammonia-lyase (3,4-dihydroxyphenylpropanoate-forming)
Comments: Forms part of the L-phenylalanine-catabolism pathway in the anoxygenic phototrophic bacterium Rhodobacter sphaeroides OU5. NADPH is oxidized more slowly than NADH.
Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number:
1. Ranjith, N.K., Sasikala, Ch. and Ramana, Ch.V. Catabolism of L-phenylalanine and L-tyrosine by Rhodobacter sphaeroides OU5 occurs through 3,4-dihydroxyphenylalanine. Res. Microbiol. 158 (2007) 506-511. [PMID: 17616348]