IUBMB Enzyme Nomenclature

EC 4.4.1.24

Accepted name: (2R)-sulfolactate sulfo-lyase

Reaction: (2R)-3-sulfolactate = pyruvate + bisulfite

Other name(s): Suy; SuyAB; 3-sulfolactate bisulfite-lyase; sulfolactate sulfo-lyase (ambigious)

Systematic name: (2R)-3-sulfolactate bisulfite-lyase (pyruvate-forming)

Comments: Requires iron(II). This inducible enzyme participates in cysteate degradation in Paracoccus pantotrophus NKNCYSA and in 3-sulfolactate degradation in Chromohalobacter salexigens. The enzyme is specific for the (R) isomer.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 1256650-35-7

References:

1. Graham, D.E. and White, R.H. Elucidation of methanogenic coenzyme biosyntheses: from spectroscopy to genomics. Nat. Prod. Rep. 19 (2002) 133-147. [PMID: 12013276]

2. Rein, U., Gueta, R., Denger, K., Ruff, J., Hollemeyer, K. and Cook, A.M. Dissimilation of cysteate via 3-sulfolactate sulfo-lyase and a sulfate exporter in Paracoccus pantotrophus NKNCYSA. Microbiology 151 (2005) 737-747. [PMID: 15758220]

3. Denger, K. and Cook, A.M. Racemase activity effected by two dehydrogenases in sulfolactate degradation by Chromohalobacter salexigens: purification of (S)-sulfolactate dehydrogenase. Microbiology 156 (2010) 967-974. [PMID: 20007648]

[EC 4.4.1.24 created 2006, modified 2011]


Return to EC 4.4.1 home page
Return to EC 4.4 home page
Return to EC 4 home page
Return to Enzymes home page
Return to IUBMB Biochemical Nomenclature home page