Reaction: L-cysteate + H2O = pyruvate + bisulfite + NH3
Glossary: L-cysteate = (2S)-2-amino-3-sulfopropanoate
Other name(s): L-cysteate sulfo-lyase (deaminating); CuyA
Systematic name: L-cysteate bisulfite-lyase (deaminating; pyruvate-forming)
Comments: A pyridoxal-phosphate protein. D-Cysteine can also act as a substrate, but more slowly. It is converted into pyruvate, sulfide and NH3. This inducible enzyme from the marine bacterium Silicibacter pomeroyi DSS-3 forms part of the cysteate-degradation pathway.
Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number:
References:
1. Denger, K., Smits, T.H. and Cook, A.M. L-cysteate sulpho-lyase, a widespread, pyridoxal 5'-phosphate-coupled desulphonative enzyme purified from Silicibacter pomeroyi DSS-3 T. Biochem. J. 394 (2005) 657-664. [PMID: 16302849]