IUBMB Enzyme Nomenclature


Accepted name: proline—tRNA ligase

Reaction: ATP + L-proline + tRNAPro = AMP + diphosphate + L-prolyl-tRNAPro

Other name(s): prolyl-tRNA synthetase; prolyl-transferRNA synthetase; prolyl-transfer ribonucleate synthetase; proline translase; prolyl-transfer ribonucleic acid synthetase; prolyl-s-RNA synthetase; prolinyl-tRNA ligase

Systematic name: L-proline:tRNAPro ligase (AMP-forming)

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, PDB, CAS registry number: 9055-68-9


1. Norton, S.J. Purification and properties of the prolyl RNA synthetase of Escherichia coli. Arch. Biochem. Biophys. 106 (1964) 147-152.

2. Peterson, P.J. and Fowden, L. Purification, properties and comparative specificities of the enzyme prolyl-transfer ribonucleic acid synthetase from Phaseolus aureus and Polygonatum multiflorum. Biochem. J. 97 (1965) 112-124.

[EC created 1972]

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