IUBMB Enzyme Nomenclature

EC 6.3.2.1

Accepted name: pantoate—β-alanine ligase

Reaction: ATP + (R)-pantoate + β-alanine = AMP + diphosphate + (R)-pantothenate

For diagram of reaction click here.

Other name(s): pantothenate synthetase; pantoate activating enzyme; pantoic-activating enzyme; D-pantoate:β-alanine ligase (AMP-forming)

Systematic name: (R)-pantoate:β-alanine ligase (AMP-forming)

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, PDB, CAS registry number: 9023-49-8

References:

1. Ginoza, H.S. and Altenbern, R.A. The pantothenate-synthesizing enzyme cell-free extracts of Brucella abortus, strain 19. Arch. Biochem. Biophys. 56 (1955) 537-541.

2. Maas, W.K. Pantothenate studies. III. Description of the extracted pantothenate-synthesizing enzyme of Escherichia coli. J. Biol. Chem. 198 (1952) 23-32.

3. Maas, W.K. Mechanism of the enzymatic synthesis of pantothenate from beta-alanine and pantoate. Fed. Proc. 15 (1956) 305-306.

[EC 6.3.2.1 created 1961]


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