IUBMB Enzyme Nomenclature


Accepted name: 5-formyltetrahydrofolate cyclo-ligase

Reaction: ATP + 5-formyltetrahydrofolate = ADP + phosphate + 5,10-methenyltetrahydrofolate

For diagram of reaction click here (another example).

Other name(s): 5,10-methenyltetrahydrofolate synthetase; formyltetrahydrofolic cyclodehydrase; 5-formyltetrahydrofolate cyclodehydrase

Systematic name: 5-formyltetrahydrofolate cyclo-ligase (ADP-forming)

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, PDB, CAS registry number: 37318-64-2


1. Greenberg, D.M., Wynston, L.K. and Nagabhushanan, A. Further studies on N5-formyltetrahydrofolic acid cyclodehydrase. Biochemistry 4 (1965) 1872-1878.

[EC created 1972]

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