Reaction: ATP + xanthosine 5'-phosphate + NH3 = AMP + diphosphate + GMP
For diagram click here.
Other name(s): xanthosine-5'-phosphate—ammonia ligase; guanylate synthetase; XMP aminase; xanthosine 5'-monophosphate aminase
Systematic name: xanthosine-5'-phosphate:ammonia ligase (AMP-forming)
Links to other databases: BRENDA, EXPASY, KEGG, CAS registry number: 9023-55-6
References:
1. Moyed, H.S. and Magasanik, B. Enzymes essential for the biosynthesis of nucleic acid guanine; xanthosine 5'-phosphate aminase of Aerobacter aerogenes. J. Biol. Chem. 226 (1957) 351-363.