Reaction: ATP + (ribonucleotide)n + (ribonucleotide)m = AMP + diphosphate + (ribonucleotide)n+m
Other name(s): polyribonucleotide synthase (ATP); RNA ligase; polyribonucleotide ligase; ribonucleic ligase
Systematic name: poly(ribonucleotide):poly(ribonucleotide) ligase (AMP-forming)
Comments: Converts linear RNA to a circular form by transfer of the 5'-phosphate to the 3'-hydroxy terminus.
Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, PDB, CAS registry number: 37353-39-2
References:
1. Silber, R., Malathi, V.G. and Hurwitz, J. Purification and properties of bacteriophage T4-induced RNA ligase. Proc. Natl. Acad. Sci. USA 69 (1972) 3009-3013. [PMID: 4342972]