INTERNATIONAL UNION OF PURE AND APPLIED CHEMISTRY
and
INTERNATIONAL UNION OF BIOCHEMISTRY AND MOLECULAR BIOLOGY

IUPAC-IUB Joint Commission on Biochemical Nomenclature (JCBN)

The Nomenclature of Steroids


(Recommendations 1989)

http://www.chem.qmul.ac.uk/iupac/steroid/

World Wide Web version prepared by G. P. Moss

Department of Chemistry, Queen Mary University of London,
Mile End Road, London, E1 4NS, UK
g.p.moss@qmul.ac.uk

The recommendations in this version are identical to those in the published document, [see Eur. J. Biochem., 1989, 186, 429-458; 1993, 213, 2; Pure Appl. Chem. 1989, 61, 1783-1822; also pages xxx-lix in Dictionary of Steroids edited R A Hill, D N Kirk, H L J Makin and GM Murphy, Chapman and Hall, London, 1991; Biochemical Nomenclature and Related Documents, 2nd edition, Portland Press, 1992, pages 192-221; Copyright IUBMB and IUPAC]. Any comments, corrections or suggestions for a future edition should be e-mailed to g.p.moss@qmul.ac.uk. A PDF of the printed version is available.

See also Kem. Kozl., 1975, 44, 543-588 (1971 version) (in Hungarian) and J.W. Morzycki, W.J. Szczepek, Nomenklatura steroidów, Wiad. Chem. Biblioteka, 1994. [ISBN 83-229-1082-7] (in Polish)

In setting up the World Wide Web version previously reported corrections have been made. The changes have been marked by error details which is a link to details of the change. For problems in converting the text into a World Wide Web version see the IUPAC home page. Any additional corrections and errors please e-mail them to g.p.moss@qmul.ac.uk or any other member of the Committee

In order to prepare the World Wide Web version the text has been divided into the following sections.

Contents and Introduction
3S-1. General
3S-2. Fundamental carbocycles, unsaturation and alkyl substitution at C-17 (3S-2.1 to 3S-2.4)
3S-2. Fundamental carbocycles, unsaturation and alkyl substitution at C-17 (continued) (3S-2.5 to 3S-2.10)
3S-3. Steroids with heterocyclic rings in the side chain
3S-4. Functional groups (3S-4.0 to 3S-4.3)
3S-4. Functional groups (continued) (3S-4.4 to 3S-4.10)
3S-5. Stereochemical modifications
3S-6. Lengthening and shortening of side chains and elimination of methylgroups
3S-7. Ring contraction and expansion
3S-8. Ring fission and 3S-9. Vitamin D group
3S-10. Additional rings and References
Appendix. Selected international non-proprietary names (INNs) of steroids
Addendum.

Pronunciation of pregn-4-ene
Numbering of Steroid Side-chain Atoms
Relevant references are quoted at the end of each section as well as all together at the end.

This document has been printed in a number of places. A full list is as follows: Nomenclature of steroids Recommendations 1989, Eur. J. Biochem., 1989, 186, 429-458; 1993, 213, 2; Pure Appl. Chem. 1989, 61, 1783-1822; Dictionary of Steroids (Hill, R.A., Kirk, D.N., Makin, H.L.J. and Murphy, G.M., eds) Chapman and Hall, London, 1991, pp xxx-lix; Biochemical Nomenclature and Related Documents,, 2nd edition, Portland Press, 1992, pp 192-221.

An extension to the rules was published in the JCBN/NC-IUB Newsletter 1992; see Biochemical Nomenclature and Related Documents,, 2nd edition, Portland Press, 1992, pp 335.

These recommendations were prepared by a working party of the IUPAC-IUB Joint Commission on Biochemical Nomenclature (JCBN), whose members were P. Karlson (chairman), J. R. Bull, K. Engel, J. Fried, H. W. Kircher, K. L. Loening, G. P. Moss, G. Popják and M. R. Uskokovic.


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