The Nomenclature of Steroids
Recommendations 1989

Appendix

Continued from 3S-10. Additional rings and References

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Selected international non-proprietary names (INNs) of steroids

INN Chemical name Molecular formula

Acrihellin 5,14-dihydroxy-3 [beta] -[(3-methylcrotonoyl)oxy]-19-oxo-5 [beta] -bufa-20,22-dienolide C₂₉H₃₈O₇

Actodigin 3 [beta] -( [beta] -D-glucopyranosyloxy)-14-hydroxy-24-nor-5 [beta] ,14 [beta] -chol-20(2)-eno-21,23-lactone C₂₉H₄₄O₉

Alfacalcidol (5Z,7E)-(1S,3R)-9,10-secocholesta-5,7,10(19)-triene-,3-diol C₂₇H₄₄O₂

Betamethasone 9-fluoro-11 [beta] ,17,21-trihydroxy-16 [beta] -methylpregna-1,4-diene-3,20-dione C₂₂H₂₉FO₅

Canrenone 3-oxo-17 [alpha] -pregna-4,6-diene-21,17-carbolactone C₂₂H₂₈O₃

Clomegestone 6-chloro-17-hydroxy-16 [alpha] -methylpregna-4,6-diene-3,20-dione C₂₂H₂₉ClO₃

Cyproterone 6-chloro-1 [beta] ,2 [beta] -dihydro-17-hydroxy-3'H-cyclopropa[1,2]pregna-4,6diene-3,20-dione C₂₂H₂₇ClO₃

Dexamethasone 9-fluoro-11 [beta] ,17,21-trihydroxy-16 [alpha] -methylpregna-1,4-diene-3,20-dione C₂₂H₂₉FO₅

Disogluside (25R)-3 [beta] -( [beta] -D-glucopyranosyloxy)spirost-5-ene C₃₃H₅₂O₈

Ethinylestradiol 19-nor-17 [alpha] -pregna-1,3,5(10)-trien-20-yne-3,17-diol C₂₀H₂₄O₂

Fluazacort 21-acetoxy-9-fluoro-11 [beta] -hydroxy-2'-methyl-16bH-oxazolo[5',4':16,17]pegna- -1,4-diene-3,20-dione C₂₅H₃₀FNO₆

Fluocortin 6 [alpha] -fluoro-11 [beta] -hydroxy-16 [alpha] -methyl-3,20-dioxopregna-1,4-dien-21-oic acid C₂₂H₂₇FO₅

Fusidic Acid (17Z)-ent-16 [alpha] -acetoxy-3 [beta] ,11 [beta] -dihydroxy-4 [beta] ,8,14-trimethyl-18-nor-5 [beta] ,10 [alpha] -cholesta- -17(20),24-dien-21-oic acid C₃₁H₄₈O₆

Gestrinone 17-hydroxy-18 [alpha] -homo-19-nor-17 [alpha] -pregna-4,9,11-trien-20-yn-3-one C₂₁H₂₄O₂

Halometasone

2-chloro-6 [alpha] ,9-difluoro-11 [beta] ,17,21-trihydroxy-16 [alpha] -methylpregna-1,4-diene-3,20-dione C₂₂H₂₇ClF₂O₅

Hydrocortisone 11 [beta] ,17,21-trihydroxypregn-4-ene-3,20-dione C₂₁H₃₀O₅

Mebolazine 17 [beta] -hydroxy-2 [alpha] ,17-dimethyl-5 [alpha] -androstan-3-one azine C₄₂H₆₈N₂O₂

Medroxyprogesterone 17-hydroxy-6 [alpha] -methylpregn-4-ene-3,20-dione C₂₂H₃₂O₃

Meproscillarin 3 [beta] -(6-deoxy-4-O-methyl- [alpha] -L-mannopyranosyloxy)-14-hydroxybufa-4,20,22-rienolide C₃₁H₄₄O₈

Mespirenone 7 [alpha] -acetylthio-15 [alpha] ,16 [alpha] -dihydro-3-oxo-3'H-cyclopropa[15,1]-17 [alpha] -pregna- -1,4-diene-21,17-carbolactone C₂₅H₃₀O₄S

Mestranol 3-methoxy-19-nor-17 [alpha] -pregna-1,3,5(10)-trien-20-yn-17-ol C₂₁H₂₆O₂

Naflocort 9-fluoro-1',4'-dihydro-11 [beta] ,21-dihydroxy-16bH-naphtho[2',3':16,17]prena- -1,4-diene-3,20-dione C₂₉H₃₃FO₄

Norenthisterone 17-hydroxy-19-nor-17 [alpha] -pregn-4-en-20-yn-3-one C₂₀H₂₆O₂

Norgesterone 17-hydroxy-19-nor-17 [alpha] -pregna-5(10),20-dien-3-one C₂₀H₂₈O₂

Norgestrel rac-17-hydroxy-18 [alpha] -homo-19-nor-17 [alpha] -pregn-4-en-20-yn-3-one C₂₁H₂₈O₂

Oxandrolone 17 [beta] -hydroxy-17 [alpha] -methyl-2-oxa-5 [alpha] -androstan-3-one C₁₉H₃₀O₃

Oxymetholone 17 [beta] -hydroxy-2-(hydroxymethylene)-17 [alpha] -methyl-5 [alpha] -androstan-3-one C₁₉H₂₈O₃

Pancuronium bromide 1,1'-(3 [alpha] ,17 [beta] -diacetoxy-5 [alpha] -androstane-2 [beta] ,16 [beta] -diyl)bis(-methylpiperidinium) dibromide C₃₅H₆₀Br₂N₂O₄

Prednisolone 11 [beta] ,17,21-trihydroxypregna-1,4-diene-3,20-dione C₂₁H₂₈O₅

Prednisone 17,21-dihydroxypregna-1,4-diene-3,11,20-trione C₂₁H₂₆O₅

Proscillardin 3 [beta] -(6-deoxy- [alpha] -L-mannopyranosyloxy)-14-hydroxybufa-4,20,22-trienolide C₃₀H₄₂O₈

Roxibolone 11 [beta] ,17 [beta] -dihydroxy-17 [alpha] -methyl-3-oxoandrosta-1,4-diene-2-carboxylic acid C₂₁H₂₈O₅

Spironolactone 7 [alpha] -acetylthio-3-oxo-17 [alpha] -pregn-4-ene-21,17-carbolactone C₂₄H₃₂O₄S

Timobesone S-methyl 9-fluoro-11 [beta] ,17 [alpha] -dihydroxy-16 [beta] -methyl-3-oxoandrosta- -1,4-diene-17 [beta] -carbothioate C₂₂H₂₉FO₄S

Triamcinolone 9-fluoro-11 [beta] ,16 [alpha] ,17,21-tetrahydroxypregna-1,4-diene-3,20-dione C₂₁H₂₇FO₆

Ursodeoxycholic acid 3 [alpha] ,7 [beta] -dihydroxy-5 [beta] -cholan-24-oic acid C₂₄H₄₀O₄

INN	Chemical name	Molecular formula
Acrihellin	5,14-dihydroxy-3-[(3-methylcrotonoyl)oxy]-19-oxo-5-bufa-20,22-dienolide	C₂₉H₃₈O₇
Actodigin	3-(-D-glucopyranosyloxy)-14-hydroxy-24-nor-5,14-chol-20(2)-eno-21,23-lactone	C₂₉H₄₄O₉
Alfacalcidol	(5Z,7E)-(1S,3R)-9,10-secocholesta-5,7,10(19)-triene-,3-diol	C₂₇H₄₄O₂
Betamethasone	9-fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione	C₂₂H₂₉FO₅
Canrenone	3-oxo-17-pregna-4,6-diene-21,17-carbolactone	C₂₂H₂₈O₃
Clomegestone	6-chloro-17-hydroxy-16-methylpregna-4,6-diene-3,20-dione	C₂₂H₂₉ClO₃
Cyproterone	6-chloro-1,2-dihydro-17-hydroxy-3'H-cyclopropa[1,2]pregna-4,6diene-3,20-dione	C₂₂H₂₇ClO₃
Dexamethasone	9-fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione	C₂₂H₂₉FO₅
Disogluside	(25R)-3-(-D-glucopyranosyloxy)spirost-5-ene	C₃₃H₅₂O₈
Ethinylestradiol	19-nor-17-pregna-1,3,5(10)-trien-20-yne-3,17-diol	C₂₀H₂₄O₂
Fluazacort	21-acetoxy-9-fluoro-11-hydroxy-2'-methyl-16bH-oxazolo[5',4':16,17]pegna- -1,4-diene-3,20-dione	C₂₅H₃₀FNO₆
Fluocortin	6-fluoro-11-hydroxy-16-methyl-3,20-dioxopregna-1,4-dien-21-oic acid	C₂₂H₂₇FO₅
Fusidic Acid	(17Z)-ent-16-acetoxy-3,11-dihydroxy-4,8,14-trimethyl-18-nor-5,10-cholesta- -17(20),24-dien-21-oic acid	C₃₁H₄₈O₆
Gestrinone	17-hydroxy-18-homo-19-nor-17-pregna-4,9,11-trien-20-yn-3-one	C₂₁H₂₄O₂
Halometasone
	2-chloro-6,9-difluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione	C₂₂H₂₇ClF₂O₅
Hydrocortisone	11,17,21-trihydroxypregn-4-ene-3,20-dione	C₂₁H₃₀O₅
Mebolazine	17-hydroxy-2,17-dimethyl-5-androstan-3-one azine	C₄₂H₆₈N₂O₂
Medroxyprogesterone	17-hydroxy-6-methylpregn-4-ene-3,20-dione	C₂₂H₃₂O₃
Meproscillarin	3-(6-deoxy-4-O-methyl--L-mannopyranosyloxy)-14-hydroxybufa-4,20,22-rienolide	C₃₁H₄₄O₈
Mespirenone	7-acetylthio-15,16-dihydro-3-oxo-3'H-cyclopropa[15,1]-17-pregna- -1,4-diene-21,17-carbolactone	C₂₅H₃₀O₄S
Mestranol	3-methoxy-19-nor-17-pregna-1,3,5(10)-trien-20-yn-17-ol	C₂₁H₂₆O₂
Naflocort	9-fluoro-1',4'-dihydro-11,21-dihydroxy-16bH-naphtho[2',3':16,17]prena- -1,4-diene-3,20-dione	C₂₉H₃₃FO₄
Norenthisterone	17-hydroxy-19-nor-17-pregn-4-en-20-yn-3-one	C₂₀H₂₆O₂
Norgesterone	17-hydroxy-19-nor-17-pregna-5(10),20-dien-3-one	C₂₀H₂₈O₂
Norgestrel	rac-17-hydroxy-18-homo-19-nor-17-pregn-4-en-20-yn-3-one	C₂₁H₂₈O₂
Oxandrolone	17-hydroxy-17-methyl-2-oxa-5-androstan-3-one	C₁₉H₃₀O₃
Oxymetholone	17-hydroxy-2-(hydroxymethylene)-17-methyl-5-androstan-3-one	C₁₉H₂₈O₃
Pancuronium bromide	1,1'-(3,17-diacetoxy-5-androstane-2,16-diyl)bis(-methylpiperidinium) dibromide	C₃₅H₆₀Br₂N₂O₄
Prednisolone	11,17,21-trihydroxypregna-1,4-diene-3,20-dione	C₂₁H₂₈O₅
Prednisone	17,21-dihydroxypregna-1,4-diene-3,11,20-trione	C₂₁H₂₆O₅
Proscillardin	3-(6-deoxy--L-mannopyranosyloxy)-14-hydroxybufa-4,20,22-trienolide	C₃₀H₄₂O₈
Roxibolone	11,17-dihydroxy-17-methyl-3-oxoandrosta-1,4-diene-2-carboxylic acid	C₂₁H₂₈O₅
Spironolactone	7-acetylthio-3-oxo-17-pregn-4-ene-21,17-carbolactone	C₂₄H₃₂O₄S
Timobesone	S-methyl 9-fluoro-11,17-dihydroxy-16-methyl-3-oxoandrosta- -1,4-diene-17-carbothioate	C₂₂H₂₉FO₄S
Triamcinolone	9-fluoro-11,16,17,21-tetrahydroxypregna-1,4-diene-3,20-dione	C₂₁H₂₇FO₆
Ursodeoxycholic acid	3,7-dihydroxy-5-cholan-24-oic acid	C₂₄H₄₀O₄

Continued in 3S addendum

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